Testing for Endocrine Diseases in Middle-Aged and Older Horses

The older equine population is at greater risk of developing debilitating endocrine disorders such as insulin dysregulation and equine metabolic syndrome, all of which are best identified and treated as early as possible.
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testing for endocrine diseases in older horses
Insulin dysregulation can occur alone or alongside clinical signs associated with other diseases. It is one of three components that constitute equine metabolic syndrome, the other two being obesity and clinical or subclinical endocrine-related laminitis. | Photo: iStock
Thanks to advances in equine health care, more horse owners find themselves in the position of managing middle-aged and older horses with careers extending well in to their 20s. This older equine population is at greater risk of developing debilitating endocrine disorders such as insulin dysregulation and equine metabolic syndrome, all of which are best treated as early as possible. As such, one Michigan State University (MSU) researcher says it’s essential that owners be aware of the signs that suggest their horses might be suffering from these conditions and to have their veterinarians screen for them during routine visits.

At the 2018 American Association of Equine Practitioners Convention, held Dec. 1-5, in San Francisco, California, Elizabeth Tadros, DVM, PhD, Dipl. ACVIM, assistant professor of endocrinology at the MSU Veterinary Diagnostic Laboratory, in Lansing, gave a rundown on these diseases and described commonly used tests for diagnosing them.

Insulin dysregulation (ID), which can plague horses of any age, is a metabolic derangement that can manifest in several ways, including:

  • Higher-than-expected insulin levels in horses that have been fasted (fasting hyperinsulinemia);
  • Higher-than-expected insulin levels after a meal (postprandial hyperinsulinemia);
  • Exaggerated responses to oral or intravenously introduced carbohydrates;
  • Tissue insulin resistance; and
  • Dyslipidemia (elevated blood lipid, or fat, levels).

Horses with ID might have one or a combination of these characteristics

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Clair Thunes, PhD, is an equine nutritionist who owns Clarity Equine Nutrition, based in Gilbert, Arizona. She works as a consultant with owners/trainers and veterinarians across the United States and globally to take the guesswork out of feeding horses and provides services to select companies. As a nutritionist she works with all equids, from WEG competitors to Miniature donkeys and everything in between. Born in England, she earned her undergraduate degree at Edinburgh University, in Scotland, and her master’s and doctorate in nutrition at the University of California, Davis. Growing up, she competed in a wide array of disciplines and was an active member of the U.K. Pony Club. Today, she serves as the district commissioner for the Salt River Pony Club.

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