b'8 STEPS FOR BREEDING YOUR MAREOvaMed (altrenogest)Solution 0.22% (2.2 mg/mL)FOR SUPPRESSION OF ESTRUS IN MARESOral ProgestinANADA 200-481, Approved by FDA CAUTIONFederal law restricts this drug to use by or on the order of a licensed veterinarian. ACTIONSOvaMed (altrenogest) produces a progestational effect in mares. INDICATIONSOvaMed is indicated to suppress estrus in mares. Suppressionofestrusallowsforapredictable occurrenceofestrusfollowingdrugwithdrawal. This facilitates the attainment of regular cyclicity during the transition from winter anestrus to the physiologicalbreedingseason.Suppressionof estrus will also facilitate management of prolonged estrus conditions. Suppression of estrus may be used to facilitate scheduled breeding during the physiological breeding season. CONTRAINDICATIONSOvaMed(altrenogest)Solution0.22%is PAM MACKENZIE contraindicated for use in mares having a previous orcurrenthistoryofuterineinflammation(i.e., acute, subacute, or chronic endometritis). Natural or synthetic gestagen therapy may exacerbate existing low-grade or smoldering uterine inflammation into a fulminating uterine infection in some instances.A breeding soundness evaluation is meant to problem-solve or to provide prognostic information, so PRECAUTIONS the owner can make informed decisions.Various synthetic progestins, including altrenogest, when administered to rats during the embryogenicKaren Wolfsdorf, DVM, Dipl. ACT,tion history and keep her current on her stageofpregnancyatdosesmanyfoldgreater than the recommended equine dose caused fetala field veterinarian and reproductivevaccines against diseases in that region, anomalies,specificallymasculinizationofthespecialist at Hagyard Equine Medicalincluding during pregnancy.female genitalia. DOSAGE AND ADMINISTRATION Institutes McGee Fertility Center, in Lex- To reduce the risk of spontaneous abor-Wearingprotectivegloves,administersolutionington, Kentucky, says one of the mosttion, the American Association of Equine orally at the rate of 1mL per 110 lbs body weight once daily for 15 consecutive days. important initial observations she makesPractitioners recommends vaccinating is the mares Henneke body conditionmares against herpesvirus-1 at five, seven, Approximate WeightDose in mL score (BCS). Ideally, broodmares shouldand nine months of gestation. On some in Pounds770 7 score between a 5 and 7 on the 1-to-10high-traffic farms, veterinarians might scale prior to breeding. administer the herpesvirus vaccine every 880 8 I like to be able to feel ribs but not seetwo months, but this is off-label use.990 9 ribs, says Wolfsdorf.1100 10 She says she also looks for protrudingStep 2: Schedule a breeding sound-1210 11 fat pads, a cresty neck, or other abnor- ness examination and address any 1320 12 malities that might suggest the mare hasproblems pituitary pars intermedia dysfunctionGetting a mare pregnant is a team WARNING (PPID, or equine Cushings disease), insu- effort between the broodmare owner and For oral use in horses only. Keep this and all other medications out of the reach of children. Do not uselin dysfunction, or some other systemicthe veterinarian, says Wolfsdorf. Vet-in horses intended for human consumption.illness that could affect the reproductiveerinarians typically perform a breeding HUMAN WARNINGS system. soundness exama reproductive exam SkincontactmustbeavoidedasOvaMed(altrenogest) Solution 0.22% is readily absorbedShe also takes into account the maresfor broodmaresto identify and manage through unbroken skin. Protective gloves must bebreeding history, including issues gettingpossible problems before breeding. worn by all persons handling this product. Pregnant women or women who suspect they are pregnantpregnant, endometritis (inflammation ofWhen discussing these exams, should not handle OvaMed (altrenogest) Solution 0.22%. Women of childbearing age should exercisethe uterine lining), or abortion.Macpherson says shes mindful of a cli-extremecautionwhenhandlingthisproduct.If the breeding will be via live cover, itsents budget and lists all the options to Accidental absorption could lead to a disruption of the menstrual cycle or prolongation of pregnancy.important to know the chosen breed- equip him or her to make an educated de-Direct contact with the skin should therefore being sheds stipulations. For example,cision on which evaluations to perform. avoided. Accidental spillage on the skin should be washed off immediately with soap and water.Wolfsdorf says some breeding shedsOften, a mare might only need a breeding PACKAGING require certain vaccinations, such as forsoundness exam if she does not conceive List No.: 1OVA007; Unit package: 1000 mL; Case size 12. rhinopneumonitis (herpesvirus-1), whichafter the first two or three attempts.* Registered mark of Bimeda 2018 veterinarians usually administer threeThe breeding soundness evalua-Bimeda, Inc. weeks to three months prior to breedingtion is far more important for the mare 1 Tower Lane, Suite 2250Oakbrook Terrace, IL 60181 USA to prevent the stallion from potentiallywith difficulty in getting pregnant or Toll Free Tel. 888-524-6332 being exposed to the virus. Wolfsdorf saysthe aged or middle-aged maiden mare, Toll Free Fax. 877-888-7035Email: [email protected] owners should know the mares vaccina- says Macpherson. I really think that a 20December 2019The Horse|TheHorse.comBreedingMares.indd 20 10/31/19 2:21 PM'