b'(Brand of Polysulfated Glycosaminoglycan (PSGAG)Adequan i.m. Three generationsprINDICATIONS For the intramuscular treatment of non-infectious degenerative and/or traumatic joint dysfunction and associated lameness of the carpal and hock joints in horses.IMPORTANT SAFETY INFORMATION There are no known contraindications to the use of intramuscular Adequan i.m.brand Polysulfated Glycosaminoglycan in horses. Studies have not been conducted to establish safety in breeding horses. WARNING: Do not use in horses intended for human consumption. Not for use in humans. Keep this and all medications out of the reach of children. CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian.Please see Full Prescribing Information at.www.adequan.com1 Adequan i.m. [package insert]. Shirley, NY: Luitpold Animal Health; 2008.2Burba DJ, Collier MA, DeBault LE, Hanson-Painton O, Thompson HC, Holder CL: In vivo kinetic study on uptake and distribution of intramuscular tritium-labeled polysulfated glycosaminoglycan in equine body fluid compartments and articular cartilage in an osteochondral defect model.J Equine Vet Sci 1993; 13: 696-703.3McIlwraith CW, Frisbie DD, Kawcak CE. The horse as a model of naturally occurring osteoarthritis. Bone Joint Res 2012; 1: 297-309.4McIlwraith CW, Frisbie DD, Kawcak CE, van Weeren PR. Joint Disease in the Horse. St. Louis, MO: Elsevier, 2016; 33-48The veterinarians at Littleton Equine Medical Center have been committed to making a difference for the horse since 1950. Over the years, Adequan i.m.has earned its place in their practice.Adequan and the Horse Head design are registered trademarksof Luitpold Pharmaceuticals, Inc.Only Adequan REVERSES the disease cycle, REPAIRS cartilage, Luitpold Animal Health, divisionRESTORES joint lubrication and REDUCES inflammation to help keepof Luitpold Pharmaceuticals, Inc. 1, 2 2017. PP-AI-US-0086 Iss. 12/2017 joints moving and horses performing.'