b'Now available!Rapid and effective fever control*1,2TheFIRSTandONLYdrugFDA-approved for control ofpyrexia in horsesFor more information, visit kindredbio.com/Zimeta.*When administered according to label directions.Zimeta is indicated for the control of pyrexia in horsesImportant Safety InformationZimeta (dipyrone injection) should not be used more frequently than every 12 hours. For use in horses only. Do not use in horses with a hypersensitivity to dipyrone, horses intended for human consumption or any food producing animals, including lactating dairy animals. Not for use in humans, avoid contact with skin and keep out of reach of children. Take care to avoid accidental self-injection and use routine precautions when handling and using loaded syringes. Prior to use, horses should undergo a thorough history and physical examination. Monitor for clinical signs of coagulopathy and use caution in horses at risk for hemorrhage. Concomitant use with other NSAIDs, corticosteroids and nephrotoxic drugs, should be avoided. As a class, NSAIDs may be associated with gastrointestinal, renal, and hepatic toxicity. The most common adverse reactions observed during clinical trials were Elevated Serum Sorbitol Dehydrogenase (SDH), Hypoalbuminemia and Gastric Ulcers. For additional information, see brief summary of prescribing information on the following page. References: 1. Zimeta (dipyrone injection). [Full Prescribing Information], Kindred Biosciences, Inc. (Burlingame, CA). Revised: 03/2019. 2. Morresey PR, et al. Randomized blinded controlled trial of dipyrone as a treatment for pyrexia in horses. Am J Vet Res. 2019;80(3):294-299.Horse Mag Zimeta FP 0120_Final.indd 1 1/29/20 3:33 PMKindred_pg.indd 1 1/27/20 3:54 PM1/29/20 3:33 PM'