Pirfenidone, a unique experimental drug with anti-fibrotic and anti-inflammatory properties, afforded no apparent therapeutic benefit in horses with experimentally-induced endotoxemia, leaving Cal Davis researchers rather disappointed.

“Previous studies led us to believe that pirfenidone would minimize the effects o

Neurectomy of the deep branch of the lateral plantar nerve resulted in a “profound” atrophy of the muscular portion of the proximal suspensory ligament reports researchers in the Equine Veterinary Journal.

The surgical procedure is routinely performed for the management of inflammation of the proximal suspensory ligament (proximal suspensory desmitis). Multiple retrospective

A novel equine influenza vaccine using a specialized second generation ISCOM-Matrix adjuvant has resulted in a product that is not only safe and effective, but also capable of closing the so-called “immunity gap,” reported researchers from Intervet/Schering-Plough Animal Health in The Netherlands.

In Europe, veterinarians traditionally administer a course of two vaccines four to

Not only can Thoroughbreds provide hours of entertainment for racing enthusiasts, they could also play an invaluable role in understanding obesity and Type 2 diabetes in humans, reports a group of Irish researchers.

“Over the past 400 years, the fastest and strongest racehorses have been selected for, resulting in the elite athletic animals we see today,” said lead researcher Emmeline

Higher levels of two different non-steroidal anti-inflammatory drugs (NSAIDs) were identified in Thoroughbred racehorses suffering musculoskeletal injuries in Kentucky Racing Commission races compared to non-injured horses. But whether these elevated levels contribute to musculoskeletal injuries or not remains to be determined, reported a group of veterinary researchers from throughout the

Advances in cytogenetic analyses using high-tech DNA-based assays have enabled researchers to look at reproductive disorders from a genetic standpoint.

Managing wounds on the lower limbs of horses is expensive, frustrating, time-consuming, and wrought with complications. Various approaches to expedite wound repair and minimize the development of serious complications have been assessed, including

New research on treating horses with equine protozoal myeloencephalitis (EPM) has found dissolving toltrazuril sulfone, commercially known as ponazuril, in dimethylsulfoxide (DMSO) instead of water prior to oral administration in horses increases the bioavailability by three times and achieves therapeutic levels in both the blood and cerebrospinal fluid.

Ponazuril and related

Despite a horse's apparently sturdy exterior, his various internal body systems are delicate–particularly his

In 2006, Ireland was rocked by an outbreak of equine infectious anemia (EIA) that was rapidly contained by veterinarians and the Irish Department of Agriculture, Fisheries and Food (read more). Despite their quick action, the fallout from this outbreak has been widespread. In the three years since the outbreak, veterinarians and

North America is free of the African horse sickness virus, yet this disease poses an important threat should an infected horse or a biting midge that harbors the virus be introduced.

African horse sickness (AHS) is the most lethal disease known to horses. Fortunately for American horses, AHS is currently enzootic, meaning