Chronic use of phenylbutazone, or Bute, in horses with joint problems could be causing more problems than it’s preventing. A recent study has shown that Bute and other non-steroidal anti-inflammatory medications (NSAIDS) might be detrimental to joint cartilage regeneration in horses.

The study was performed by Lisa Beluche, DVM; Alicia Bertone, DVM, PhD, Dipl. ACVS; David Anderson, DVM; and Carsten Rohde, DVM; of The Ohio State University’s (OSU) Orthopedic Research Laboratory, and appeared in a recent issue of the American Journal of Veterinary Research. Eleven sound and radiographically normal 18- to 30-month-old horses were used in the study

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