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Endotoxemia is a serious condition resulting from the presence of endotoxin in a horse’s blood. It has several causes, ranging from retained fetal membranes after foaling to colic to skin infections and can lead to shock, laminitis, and even death..
Endotoxemia. Septic shock. Intestinal ischemia. What do all these ailments have in common? Based on recent studies, some researchers think an investigational drug called pirfenidone might be a treatment option for all three.
Endotoxemia occurs when toxins from the wall of Gram-negative bacteria crosses the intestinal wall and gains access to the bloodstream. Endotoxin becomes concentrated on the surface of white blood cells, causing them to secrete inflammatory agents.
Endotoxemia is one of the most commonly encountered life-threatening conditions in horses with gastrointestinal disease. It is, by nature, a very disappointing and frustrating disease to encounter, and is the leading cause of death in adult horses
A total of 2,351 equine veterinarians–a record attendance–descended on Lexington for the 41st annual American Association of Equine Practitioners convention. Committee business dominated the day on Dec. 2, with 21 of the association’s 40
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