The stallion worked July 5 before developing colic and endotoxemia that night. He remains in intensive care.
Endotoxemia. Septic shock. Intestinal ischemia. What do all these ailments have in common? Based on recent studies, some researchers think an investigational drug called pirfenidone might be a treatment option for all three.
Endotoxemia occurs when toxins from the wall of Gram-negative bacteria crosses the intestinal wall and gains access to the bloodstream. Endotoxin becomes concentrated on the surface of white blood cells, causing them to secrete inflammatory agents.
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