As the 2025 Equine Sports Medicine Symposium places a spotlight on metabolic disease, EZium is proud to support the event and introduce veterinarians and equine professionals to EZium Metabolic — a science-backed nutritional supplement that contains ingredients backed by over 20 years of research to support horses facing metabolic dysfunction, chronic stress, and related health complications.

EZium Metabolic combines highly bioavailable chelated magnesium glycinate with FDA-reviewed chromium propionate to optimize glucose metabolism, replenish glycogen stores, regulate cortisol, and reduce the negative impacts of stress on the equine body. 

“Our goal with EZium Metabolic is to offer targeted support for horses that are struggling with insulin resistance, laminitis, obesity, or stress-related complications,” said Dr. Teena Middleton, founder of EZium. “By providing a supplement that contains ingredients proven to address both metabolic and hormonal factors, we can help improve overall health, recovery, and performance.” 

The Science of Glucose Utilization 

Every cell in the horse’s body relies on glucose to fuel its function and growth. Magnesium and chromium work together to unlock the glucose absorption pathway into the cells, increasing glucose uptake across tissues. This is particularly important for skeletal muscle, where replenished glycogen stores translate to improved energy availability and better physical performance. 

Low muscle glycogen levels can significantly impair recovery and stamina. By enhancing cellular glucose absorption, the nutrients in EZium Metabolic helps restore energy reserves and maintain consistent output during work or competition. 

Moreover, activated immune cells rely exclusively on glucose for energy, especially during immune responses to disease or environmental challenges. Supporting glucose uptake may therefore improve the horse’s ability to mount a defense against illness, even under pressure. 

Stress, Cortisol, and Chromium’s Critical Role

In times of stress — whether physical, psychological, or environmental — the horse’s body releases cortisol, a hormone that not only raises blood sugar but also suppresses immunity, impairs digestion, and increases the risk of gastric ulcers, colic, and diarrhea. 

The demand for chromium can spike up to 300 times higher during these stress events, often leaving horses depleted and more vulnerable to health consequences. 

EZium Metabolic supplies chromium propionate, the only FDA-reviewed form of chromium for animal use, which has been clinically shown to reduce serum cortisol. Lower cortisol means fewer of the downstream complications associated with stress, and better recovery following high-stakes exertion or emotional strain. 

Heat Tolerance and Metabolic Resilience 

Emerging evidence also suggests that increased glucose uptake improves thermal tolerance in heat-stressed animals. For performance horses competing or training in hot climates, the metabolic benefits of the nutrients in EZium Metabolic may support not just recovery, but resilience under pressure. 

“Metabolic health isn’t just about managing disease — it’s about enabling horses to thrive under physical, environmental, and emotional stressors,” Dr. Middleton added. “That’s what EZium Metabolic is built to do.” 

Optimized Ingredients for Maximum Benefit 

EZium products set themselves apart with the use of magnesium glycinate, a chelated form of magnesium bound to glycine that offers up to four times the bioavailability of more common forms like magnesium oxide or magnesium citrate. 

Chelated minerals are gentler on the gut and absorbed more efficiently, making them a better long-term option for horses needing daily support. 

The formula is delivered as a highly palatable pellet, available in resealable packaging sized for 1‑, 2‑, or 4‑month supply. It contains no substances banned by any equine governing body, and is produced here in the USA. 

“By optimizing glucose utilization, regulating cortisol, and restoring essential nutrients, we’re providing essential nutrients that help horses not just survive metabolic stress — but actually thrive in spite of it,” Dr. Middleton said. 

About EZium 

E-Z Equine is an equine supplement company dedicated to providing highly bioavailable, safe, and effective magnesium-based formulas for horses. Founded by a lifelong horsewoman with a passion for science-backed solutions, EZium uses chelated magnesium glycinate—absorbed more than four times better than standard magnesium sources—to support metabolic health, reduce the negative impacts of stress, and optimize performance. EZium products are proudly manufactured in the USA and trusted by veterinarians, trainers, and riders across disciplines. For more information, visit www.EZium.org