As part of its strategic initiative to protect the health and welfare of the racehorse, the American Association of Equine Practitioners (AAEP) has released a list of research topics identified by a panel as central to the goal of understanding exercise-induced pulmonary hemorrhage (EIPH).

The identified topics will help determine future research priorities in the investigation of alternative management strategies for EIPH.

The panel, assembled for an AAEP-hosted meeting in November 2015, included experts in the fields of equine EIPH, pulmonary and cardiac physiology, lung pathology, and human sports medicine. Their focus was a review of current scientific knowledge and the identification of future research priorities.

Examined topics included epidemiology, vascular physiology, pathology, venous remodeling, role of the heart, pathophysiology of blood flow, efficacy of furosemide and regenerative medicine in the lung.

“The racehorse is a superb athlete bred for maximal performance and the panel recognized the physiological challenges of eliminating all occurrences of EIPH,” said Kathy Anderson, DVM, the 2016 AAEP president. “It is clear, however, that our body of existing research has not yielded the information needed to develop more effective treatment options. The questions far outweigh the answers.”

The following research topics were considered by the panel as important to the goal of understanding EIPH:

  • Experimentally validate the contributions of pulmonary arterial and venous pressures and decreased alveolar pressures to EIPH and to subsequent lung lesions;
  • Characterize the v