The most common fatal injury in racehorses in the United States, PSB fractures account for 45-50% of such injuries in Thoroughbreds and 37-40% in racing Quarter Horses. The PSBs are two comparatively small bones located in the fetlock that act as part of the suspensory apparatus. Fractures in these bones are likely due to the accumulation of repeated, stress-related processes. This is supported by evidence that racehorses in intensive training are at higher risk for PSB fractures, but the exact causes are not well understood.
Other repetitive overuse injuries in horses are known to be bilateral in nature, meaning they are similar on both sides of the horse, with the more severely affected limb usually incurring the fracture. With this in mind, the researchers looked at both the fractured PSB and the intact PSB from the opposing limb of the same horse for all cases. They hypothesized that horses with PSB fractures would also show evidence of stress in the PSB of the opposite limb and that the bone that sustained the break would show more severe changes than the intact bone.
The results showed that 90% of the fractured PSBs had visible discoloration on the surface of the fracture, most commonly (70% of the time) in a characteristic crescent pattern. Directly below the cartilage, the researchers noted evidence of bone loss in 70% of cases. This bone loss was in the same region as the discolorations. Fractured PSBs had lower bone volume fraction and tissue mineral density within the lesion sites than comparable locations in opposing limbs and controls. These regions were contiguous with the fracture lines. They also observed evidence of microdamage in fractured PSBs.
Overall, the team identified more changes in the bones of the case horses than control horses, and these changes were more severe in the fractured limbs than in the opposing limbs. Sampling from areas of bone distant from the lesions revealed no significant differences in bones from case and control horses other than the presence of a lesion.
This data support the role of microdamage and tissue remodeling in the formation of lesions in PSBs. It is important to note that all the horses in this study were California racehorses, so it is currently unknown if the results will apply equally to racehorses in other areas. Future studies with larger sample sizes might provide further information.
Understanding the mechanism of PSB fracture is necessary to determine risk factors and prevent fractures. Combining this information with advanced technology, such as the recent introduction of positron emission tomography (PET scan), might help veterinarians identify horses at risk of PSB fracture and inform management alterations to avoid injury.