Rediscover the partnership with Zyoglide®.
Peppermint-flavored pergolide tablets to support consistent daily use.
360-degree, half-scored tablet for accurate dosing.
Zygolide® delivers clinical results you need with the practical benefits that support daily care.
PPID is a lifelong disease, which makes consistent treatment critical.
Cost-effective treatment1.
Help your horse feel their best so you can enjoy more happy moments together.
IMPORTANT SAFETY INFORMATION: As with all drugs, side effects may occur. Zygolide® (pergolide tablets) is for use in horses only. Zygolide has not been evaluated in breeding, pregnant or lactating horses. Treatment with Zygolide may cause loss of appetite. Most cases are mild. If severe, a temporary dose reduction may be necessary. Weight loss, lack of energy, and behavioral changes also may be observed. Zygolide tablets should not be crushed due to the potential for increased human exposure. Pregnant or lactating women should wear gloves when administering this product. Zygolide is contraindicated in horses with hypersensitivity to pergolide mesylate or other ergot derivatives. Keep Zygolide in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose. Dogs have eaten pergolide tablets that were placed in food intended for horses or dropped during administration of the tablets to the horses. Adverse reactions may occur if animals other than horses ingest Zygolide tablets. Refer to the prescribing information for complete details or visit www.zygolide.com.
1. Pricing based on www.valleyvet.com; March 4, 2026.