Laminitis (commonly called “founder”) affects an estimated 7-14% of the world’s equine population. It’s the inflammation of the tiny, interwoven lamellae that attach a horse’s hoof to the underlying coffin bone (third phalanx, or P3) and support the horse’s entire body weight. Anything that impacts the integrity of the lamellae, such as inflammation, weakens their hold. This causes the coffin bone to displace within the hoof capsule and move toward the ground. The condition is very painful and is often life-threatening to horses.
The same disease has several different causes, which include:
The purpose of our study was to determine if plasmid-mediated gene therapy in combination with electroporation was possible in the horse, particularly for the treatment of clinically important diseases such as laminitis.
Equine veterinarians have known for years that some horses can handle the spring grass, while others will become ill and develop laminitis, a painful disease process in which the hoof wall separates from its attachments in the foot.
Barbaro first captured America’s imagination, then its heart.
Acidosis (abnormally high acidity) in the hindgut (the large intestine and colon) can cause a number of problems in horses, including anorexia, colic, laminitis, and stereotypic (continuous, repetitive, and serving no purpose) behaviors such as
To find ways to better manage pain in horses, researchers have been studying a technique that involves inserting continuous peripheral nerve block (CPNB) catheters along nerves in the horse’s front limb to relieve pain.
Insulin resistance, the body’s inability to control blood sugar levels with normal amounts of insulin, is known to be associated with equine obesity, altered reproductive function, and pasture-associated laminitis. In addition, insulin resistance
The white wooden fence once tacked with homemade signs expressing prayers and appeals to “Grow, Hoof, Grow” are bare. Only students pass through the lobby that overflowed with floral arrangements, get-well cards, and baskets stuffed with carrots an
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A devastating disease made a household word by a famous horse, laminitis is an inflammatory and extremely painful condition affecting the soft tissues between the hoof and coffin bone (laminae). This condition, which eventually claimed the life
The principle behind using a buffer solution to stave off laminitis is based on acidity of the equine gut and its effects on enzyme activity. When a horse gets an overload of carbohydrate, the acidity in his gut increases dramatically due to ferment
Nearly 800 readers of TheHorse.com responded to a poll asking, “What have you seen used to diagnose and evaluate laminitis at the onset and throughout the treatment period?”
