Information on pituitary pars intermedia dysfunction (PPID), also known as Cushing’s Disease in horses.
Pituitary pars intermedia dysfunction–PPID, or Cushing’s disease–is the most common disease of horses and ponies 15 years of age or older. Although it’s not fully understood yet, researchers are learning more about how to treat and prevent it.
Unfortunately, no perfect PPID test (one that is 100% accurate with a single-sample test) yet exists. At the 2006 AAEP Convention, Harold Schott, DVM, PhD, Dipl. ACVIM, professor of large animal clinical sciences at Michigan State University,
We know Cushing’s disease (or pituitary pars intermedia dysfunction?PPID?as it’s more scientifically called), simply put, is an “old-horse disease” that results in metabolism disturbances and an abnormally heavy hair coat. But when it comes to
The Food and Drug Administration’s (FDA) Center for Veterinary Medicine announced on May 11 it will allow bulk pergolide to be used in compounding pergolide for use in horses.
Pergolide mesylate, a drug commonly used to treat pituitar
More than a month after pergolide mesylate, a drug commonly used to treat pituitary pars intermedia dysfunction (PPID), also known as equine Cushing’s disease, was withdrawn for human use, the FDA has yet to make an announcement on whether
Pergolide mesylate, a drug commonly used to treat pituitary pars intermedia dysfunction (PPID), also known as equine Cushing’s disease, has been withdrawn for human use. The FDA made this announcement March 29. Since that time, horse owners and
The FDA has announced pergolide is to be voluntarily withdrawn for human use. Pergolide is commonly used for horses with pituitary pars intermedia dysfunction (PPID), also known as equine Cushing’s disease.
According to the FDA announcement
Adipobiology (The Study of Fat in the Body): An Emerging Field
A group of veterinarians gathered at the Land O’ Lakes Purina Mills headquarters in St. Louis, Mo., last fall to participate in discussions on subjects that ranged from Cushing’s disease to proper nutrition for horses young and old. Nicholas Frank,
Fresh from the AAEP Annual Convention, here’s an update on what we know about these two disorders and how to manage them:
Equine metabolic syndrome typically affects horses aged 8 to 18-years-old. Pony breeds, domesticated Spanish
In the horse, the hormone dopamine exerts a number of effects through its actions on the pituitary gland. Both dopamine and ergovaline, a dopaminergic agonist (a drug that stimulates dopamine receptors), can significantly impact the mare’s
It’s spring, yet your aging equine has failed to shed his long, shaggy, winter coat. Furthermore, he’s developed a saggy belly coupled with loss of muscle over his croup and rump. He’s gulping down far more water than he used to, and his stall i
I have an older Tennessee Walking Horse with Cushing’s disease. She has been on Cipro for some time. She foundered…
Equine metabolic syndrome (EMS), Cushing’s disease, insulin resistance (IR), glucose intolerance, and glycemic indices of feeds have gotten a lot of press lately. The terms are taken from the human literature, where they have very specific
Could something in the environment be predisposing my horses to Cushing’s syndrome?
Hormone Responses to Feeds
Joe Pagan, PhD, owner of Kentucky Equine Research in Versailles, Ky., discussed glycemic response in growing horses as an indicator of developmental orthopedic disease. He said looking at diet and
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