If you thought methicillin-resistant Staphylococcus aureus (MRSA) was bad news for horses and their human connections, there’s something even uglier you might want to learn about. There’s a new "superbug" in town, and although it hasn’t yet infected horses, it isn’t to be taken lightly.

New Delhi metallo-beta-lactamase-1 (NDM-1) is an enzyme capable of neutralizing antibiotics. Researchers have found this enzyme can neutralize not only most beta-lactam antibiotics (such as penicillin), but also some "big-gun" antibiotics (such as imipenem), which are sometimes used to treat drug-resistant infections.

Bacteria that produce NDM-1 include members of the Enterobacteriaceae family (such as Escherichia coli). These bacteria produce NDM-1 and therefore are likely resistant to multiple antibiotics, and the NDM-1 gene appears to be easily transferred to other members of the Enterobacteriaceae family.

Since the first human case was diagnosed in 2009, NDM-1-producing Enterobacteriaceae have been found in the United States, Canada, France, Japan, and Australia, among other locations

Create a free account with TheHorse.com to view this content.

TheHorse.com is home to thousands of free articles about horse health care. In order to access some of our exclusive free content, you must be signed into TheHorse.com.

Start your free account today!

Already have an account?
and continue reading.