Compounding Study: Know What You’re Getting

A recent study showed that one type of compounded omeprazole was ineffective against gastric ulcers in horses.
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A recently published study showed that administration of one type of compounded omeprazole suspension was ineffective in healing ulcers in racehorses, while treatment with the FDA-approved form of omeprazole (GastroGard) was effective in attenuating ulcers. The study was completed at the University of California, Davis, and appeared in the latest issue of the Journal of the American Veterinary Association (  Findings show that horse owners trying to save money by using the particular compound used in the study aren’t helping their horses, and should spur horse owners to find out what’s in compounded medications they purchase. 



Endoscopic views of the same horse exhibiting severe stomach ulcers at pre-trial examination (left), significant healing after 30 days of treatment with GastroGard (center), and the recurrence of ulcers after treatment was switched to compounded omeprazole for an additional 30 days (right)

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Written by:

Stephanie L. Church, Editorial Director, grew up riding and caring for her family’s horses in Central Virginia and received a B.A. in journalism and equestrian studies from Averett University. She joined The Horse in 1999 and has led the editorial team since 2010. A 4-H and Pony Club graduate, she enjoys dressage, eventing, and trail riding with her former graded-stakes-winning Thoroughbred gelding, It Happened Again (“Happy”). Stephanie and Happy are based in Lexington, Kentucky.

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