(Author’s note: Sera, Inc., who markets oral and IV equine IgG products approved by the USDA, sponsored a roundtable discussion on Biological Solutions for Biological Problems in Lexington, Ky. Participating in the roundtable were: Michelle LeBlanc, DVM, of the University of Florida, who acted as moderator; William V. Bernard, DVM, Diplomate American College of Veterinary Internal Medicine, a partner in the Rood and Riddle Equine Hospital near Lexington; Jonathan Davis, DVM, resident veterinarian at Milfer Farm, Unadilla, NY; Dan Watkins, DVM, a general equine practitioner from Weatherford, Texas; and Oscar Swanson, DVM, a racetrack practitioner from Louisville, Ky. Following are excerpts and discussions from the roundtable.)

The topics covered in the roundtable on Biological Solutions for Biological Problems included failure of passive transfer (also see The Horse of February 1996, page 37), treatment of Rhodococcus equi in foals; exercise-induced pulmonary hemorrhage, and general use of oral IgG.

Dan Watkins, DVM, said at his clients’ farms, tests are run on foals for IgG, and immunotherapy is utilized for that and to try and prevent Rhodococcus equi. He said in years past, plasma was given to foals which were at risk of failure of passive transfer (FPT). Recently, however, he had been using oral IgG (Seramune) on the foals prophylactically before they first nurse. He said the product is given orally, and the first dose is the easiest to administer because the foals will suckle it out of the syringe. He said the next two doses are more difficult to administer because the foals have had a taste of milk and don’t like the product as well.

Watkins said his initial dose was 150 cc, followed by two doses of 150 cc each two hours apart.

“The farms I deal with have mares sent off the farm to be bred,” Watkins said. “We find it a benefit to check the