Topical Atropine Not Likely Linked to Colic Development
No account yet? Register
“Inflammation in the eye, particularly long-term inflammation, can become very serious and threaten the health and visual capabilities of the eye,” said Heather Chandler, PhD, an associate professor at The Ohio State University College of Optometry, in Columbus. “Minimizing ocular inflammation and pain can improve both the comfort and prognosis of the eye.”
However, oral atropine has been associated with slowed gastrointestinal movement and, thus, an increased colic risk. Therefore, some veterinarians and researchers have expressed concern that the topical ocular solution might also cause changes to the horse’s digestive system. Still, there was no published data objectively indicating that ocular atropine can decrease gastrointestinal motility.
Chandler and colleagues recently set out to explore the potential connection between the use of topical atropine and gut motility. The researchers randomly assigned six healthy geldings to one of two groups and administered a topical treatment to the left eye (either 1% atropine or artificial tears) left the right eye untreated. For the first day, the researchers treated the horses every six hours, then reduced treatment to every 12 hours for four more days. After a four-week washout period, the horses received the opposite treatment in the left eye; the right eye remained untreated
Create a free account with TheHorse.com to view this content.
TheHorse.com is home to thousands of free articles about horse health care. In order to access some of our exclusive free content, you must be signed into TheHorse.com.
Start your free account today!
Already have an account?
and continue reading.
Related Articles
Stay on top of the most recent Horse Health news with