The American Veterinary Medical Association (AVMA) has offered input to help smooth implementation of proposed new federal guidelines on a useful and effective induction agent, propofol.

The Drug Enforcement Agency (DEA) has proposed making propofol a Schedule IV drug (drugs that have a safe and accepted medical use in the United States, including those certain narcotic and non-narcotic drugs, anti-anxiety drugs, tranquilizers, sedatives, stimulants, and non-narcotic analgesics). In a letter to the DEA Dc. 21, the AVMA has offered input to help the DEA keep this effective drug, which typically causes few side effects when used appropriately in patients, in use in veterinary clinics while keeping it out of the hands of abusers.

"The DEA cites research that 28 percent of drug abusers of propofol die as a result of this abuse, so the AVMA understands the DEA's actions to stop diversion of propofol from its intended use," explains Ron DeHaven, DVM, chief executive officer of the AVMA. "However, propofol is also an effective drug used in veterinary anesthesia, and we want to make sure that the burden of disposing of it under the DEA's rules doesn't discourage veterinarians from utilizing propofol."

Unlike many other drugs, preservative-free propofol has a very short shelf life, meaning that it becomes unusable within hours of opening. The AVMA is concerned that under DEA rules, veterinarians may no longer be allowed to dispose of any unused propofol into an absorbent substance for incineration or disposal as solid waste