Blood Biomarkers Could Help Diagnose Sarcoids in Horses

Veterinarians might soon be able to diagnose sarcoids in horses using a simple blood test rather than an invasive biopsy. Here’s what researchers are studying.
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sarcoids in horses
Is that patch of rough-looking skin or little warty lump a sarcoid? Researchers are working to develop a blood test to aid in diagnosing sarcoids in horses. | Photo: Alexandra Beckstett/The Horse

Sometimes it’s obvious your horse has a sarcoid—those skin tumors with a classic nodular or verrucous (cauliflowerlike) appearance are difficult to miss. But what about that patch of rough-looking skin or that little warty lump? Are they sarcoids? Your veterinarian can run diagnostic tests for sarcoids in horses, but those techniques aren’t without their challenges. Gold-standard biopsies can aggravate the tumors and make the disease worse, and less-invasive swabbing techniques don’t detect all cases.

But researchers in Switzerland are working toward a new way to confirm sarcoids: They’ve tested an innovative blood test that looks for recently identified biomarkers indicative of sarcoids.

The focus is on microRNAs (miRNAs)—tiny RNAs that circulate freely in the blood without cells and don’t code for anything, but seem to target and silence messenger RNAs, said Lucia Unger, DrMedVet, Dipl. ECEIM, and Vinzenz Gerber, DrMedVet, PhD, Dipl. ACVIM, ECEIM, both of the University of Bern Vetsuisse Faculty Swiss Institute of Equine Medicine and Agroscope Bern

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Passionate about horses and science from the time she was riding her first Shetland Pony in Texas, Christa Lesté-Lasserre writes about scientific research that contributes to a better understanding of all equids. After undergrad studies in science, journalism, and literature, she received a master’s degree in creative writing. Now based in France, she aims to present the most fascinating aspect of equine science: the story it creates. Follow Lesté-Lasserre on Twitter @christalestelas.

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