Researchers Assess Deworming’s Link to Inflammation in Horses

“Concerns have been raised that killing larvae while encysted within the mucosal walls could lead to adverse (e.g., inflammatory) reactions,” said Ashley E. Steuer, DVM, PhD, assistant professor of parasitology at Texas Tech University’s School of Veterinary Medicine, in Amarillo.
She and a team from the University of Kentucky recently performed a study to assess horses’ inflammatory response to deworming. “We were especially keen on evaluating the difference between a product that kills those pesky encysted larvae (moxidectin) and a product that does not (ivermectin),” Steuer said. She presented their findings at the 2020 American Association of Equine Practitioners’ virtual convention.
“It’s important that we discuss this inflammatory response, because this can cause disease—not necessarily the parasites themselves, but the reaction to their existence within the host,” Steuer said, adding that very few studies have looked at post-deworming inflammation in horses
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